منابع مشابه
Hepatocellular carcinoma: when is liver transplantation oncologically futile?
Selection criteria of patients with hepatocellular carcinoma (HCC) for liver transplantation (LT) have been progressively expanded since the introduction of the Milan criteria. Transplanting patients with unfavourable tumor characteristics increases the risk of tumor recurrence and impacts post-transplant survival. Although tumor number and size are the basis of widely accepted selection criter...
متن کاملWhen is a patient too well and when is a patient too sick for a liver transplant?
1. Liver transplantation is currently offered as a therapeutic option for patients with a wide range of end-stage liver diseases. 2. Conventional wisdom suggests that patients who receive a liver transplant have a greater expected lifetime when compared to comparable candidates on the waiting list. 3. The model for end-stage liver disease (MELD) scoring system is an excellent predictor of morta...
متن کاملWhen will resistance be futile?
Cancer cells rapidly evolve a multitude of defense mechanisms to evade the effects of the oncologist's drug arsenal. Unfortunately, clinical strategies to overcome these lag far behind. This mismatch likely underlies our inability to implement new durable treatment strategies. Here, a new form of multidrug resistance, inducible drug glucuronidation, is discussed. This form was discovered while ...
متن کاملCirrhosis and operative trauma: determining when care is futile
s from the First Annual Baylor Scott and White Surgery Research Day 318 was that maternal preeclampsia independently increases necrotizing enterocolitis (NEC) risk in newborns. Th e database of all births at our institution from 2008 to 2011 (n = 9993) was retrospectively reviewed after institutional review board approval. Multiple mother and baby variables, including maternal age, race, parity...
متن کاملPediatric Liver Transplant
The goals of post-transplant management are to manage and treat postoperative complications, and develop a balanced long-term immunotherapy regimen that minimizes infection and side effects but controls rejection. While modern immunosuppressant regimes have reduced rates of graft loss due to rejection, they impart major risks for infection, growth failure, metabolic complications, and malignanc...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2008
ISSN: 1527-6465,1527-6473
DOI: 10.1002/lt.21515